Modern cities face an invisible challenge stemming from our built environment's materials. The industrial revolution brought forth new construction materials that, while economically efficient, have created an unprecedented shift in our environmental microbiome. These materials, developed within the last 150 years, host what microbiologists term "new friends" - novel microorganisms that have adapted to thrive on synthetic surfaces. Unlike our "old friends," microorganisms we've co-evolved with for over 200,000 years, these new microbial communities often trigger adverse physiological responses in humans.

The metabolic processes of these "new friends," particularly those thriving on plastics and industrial chemicals, produce compounds that can provoke various inflammatory responses in human bodies. From respiratory issues like allergies and asthma to more severe chronic inflammatory and autoimmune disorders, the impact of this altered urban microbiome presents a significant public health challenge.

Embryogenesis addresses this challenge through an innovative approach to ecological public spaces. The initiative implements a network of interconnected parks and rooftops that leverage native wildlife and natural air circulation to reintroduce beneficial microbiome elements throughout urban areas. By reconceptualizing rooftop parks as urban canopy layers, this system creates a multi-tiered approach to ecological infrastructure, where each level serves distinct environmental functions.

This design philosophy recognizes birds (both resident and migratory), pollinating insects, and small mammals as crucial stakeholders in urban infrastructure. These creatures become natural vectors for beneficial microbiome distribution, creating a "living metabolism" within the city - a concept that translates readily into traditional urban planning frameworks focused on flow and circulation.

This paradigm shift enables the development of Biologically Integrated Smart Cities, where ecological flows can be monitored and managed with the same precision as traditional urban metrics. By integrating real-time data collection and analysis of taxonomical and metagenomic information, cities can actively manage their microbiome health, much like they currently monitor other smart city parameters. This approach transforms public spaces from mere recreational areas into active interventions against urban inflammation, creating healthier, more resilient urban environments.